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Search Results for " granulocyte colony-stimulating factor "

Targets Recommended: Proteasome DPP-4

9

抑制剂 & 化合物

26

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T4042	Talabostat mesylate Val-boroPro,PT100	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Talabostat mesylate (PT100) 是一种具有口服活性和非选择性的二肽基肽酶 IV 抑制剂(IC50< 4 nM;Ki= 0.18 nM)。Talabostat mesylate 是成纤维细胞活化蛋白的第一个临床抑制剂(IC50= 560 nM)，抑制 DPP8/9 (IC50= 4/11 nM;Ki= 1.5/0.76 nM)，静息细胞脯氨酸二肽酶(IC50= 310 nM)、DPP2 和一些其他 DASH 家族酶。Talabostat mesylate 具有抗肿瘤和造血刺激活性。
T80585	Anti-Mouse GM-CSF Antibody (MP1-22E9)	c-Fms	Tyrosine Kinase/Adaptors
	Anti-MouseGM-CSFAntibody 为特异性针对小鼠GM-CSF的IgG2a类免疫球蛋白抗体，由大鼠血清中提取。
T82924	Balugrastim CG 10639
	Balugrastim (CG 10639)为新型长效G-CSF，由重组人血清白蛋白与G-CSF遗传融合制成，适用于乳腺癌研究。
T76908	Anumigilimab
	Anumigilimab (CSL-324) 是一种人源化IgG2a 单抗，靶向人粒细胞集落刺激因子 (G-CSF) 受体。Anumigilimab 可用于炎症部位中性粒细胞数量增加的研究。
T38384	Nexinhib20
	Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony-stimulating factor (GM-CSF) and fMLP in isolated human neutrophils (IC50 = 0.33 μM). Nexinhib20 (30 mg/kg) reduces LPS-induced increases in plasma MPO levels, as well as LPS-induced hepatic and renal neutrophil infiltration in a mouse model of endotoxin-induced systemic inflamma...
T73659	HLF1-11
	HLF1-11，一种人乳铁蛋白衍生肽，是一种广谱抗菌剂。HLF1-11 抑制MPO(human) 的活性。HLF1-11 还使GM-CSF 驱动的单核细胞向巨噬细胞分化，并增强其免疫反应。
T78328	Efbemalenograstim alfa F 627,Bineuta,Benegrastim
	Efbemalenograstim alfa（F 627）为重组长效二聚体G-CSF，融合了两个人源G-CSF与人免疫球蛋白G2（hIgG2）-Fc片段，并能有效促进白细胞生成。
T79149	Magmas-IN-1	Others	Others
	Magmas-IN-1（compound 9）为针对Magmas的小分子抑制剂（SMMI），后者是线粒体相关粒细胞-巨噬细胞集落刺激因子（GM-CSF）的信号分子，并参与骨髓细胞的GM-CSF诱导基因表达。Magmas-IN-1作用于Magmas，进而调控线粒体功能，并在4 μM浓度下可显著抑制酵母细胞的增殖。
T77172	Eflapegrastim
	Eflapegrastim 是一种人源化IgG4单抗，也是一种粒细胞集落刺激因子 (G-CSF)。Eflapegrastim 靶向G-CSF 受体 (c-Fms)。Eflapegrastim 刺激中性粒细胞祖细胞的增殖和分化，维持成熟和功能性中性粒细胞数目稳定。Eflapegrastim 还缩短中性粒细胞减少的持续时间。

化合物

Talabostat mesylate

Cat.No: T4042

Synonym: Val-boroPro,PT100

Target: Proteasome, DPP-4

Anti-Mouse GM-CSF Antibody (MP1-22E9)

Cat.No: T80585

Target: c-Fms

Cat.No: T82924

Synonym: CG 10639

Cat.No: T76908

Cat.No: T38384

Cat.No: T73659

Efbemalenograstim alfa

Cat.No: T78328

Synonym: F 627,Bineuta,Benegrastim

Cat.No: T79149

Target: Others

Cat.No: T77172

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03713	GM-CSF/CSF2 Protein, Rat, Recombinant (His) colony stimulating factor 2 (...	Rat	HEK293 Cells
	GM-CSF/CSF2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P48750.
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) Colony-Stimulating Factor,CSF2,CS...	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo...
TMPY-04829	G-CSF Protein, Human, Recombinant G-CSF,colony stimulating factor 3...	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPY-00750	GM-CSF/CSF2 Protein, Human, Recombinant (hFc) 集落刺激因子,CSF2,GM-CSF,colony stimulating ...	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is P04141.
TMPY-03662	GM-CSF/CSF2 Protein, Mouse, Recombinant (His) GMCSF,MGI-IGM,colony stimulating facto...	Mouse	HEK293 Cells
	GM-CSF/CSF2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.10 kDa and the accession number is P01587.
TMPY-05636	G-CSF Protein, Mouse, Recombinant G-CSF,MGI-IG,Csfg,集落刺激因子,colony stimulating	Mouse	HEK293 Cells
	G-CSF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19 kDa and the accession number is P09920.
TMPY-03858	GM-CSF/CSF2 Protein, Human, Recombinant CSF2,colony stimulating factor 2 ...	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141.
TMPY-02312	CSF3R/G-CSFR Protein, Human, Recombinant (His) CSF3R,GCSFR,colony stimulating factor<...	Human	HEK293 Cells
	CSF3R/G-CSFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is Q99062-1.
TMPY-01650	CD131 Protein, Human, Recombinant (His) CDw131,IL5RB,colony stimulating factor...	Human	HEK293 Cells
	CD131 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P32927-1.
TMPY-04114	GM-CSF/CSF2 Protein, Mouse, Recombinant MGI-IGM,colony stimulating factor...	Mouse	HEK293 Cells
	GM-CSF/CSF2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.1 kDa and the accession number is P01587.
TMPY-01065	GM-CSFR alpha Protein, Human, Recombinant (His) GM-CSF-R-α,colony stimulating factor	Human	HEK293 Cells
	GM-CSFR alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P15509-1.
TMPY-04036	GM-CSF/CSF2 Protein, Rat, Recombinant (hFc) 集落刺激因子,colony stimulating factor ...	Rat	HEK293 Cells
	GM-CSF/CSF2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is P48750.
TMPJ-00091	G-CSF Protein, Mouse, Recombinant (His) Csf3,G-CSF,Granulocyte colony-stimulat...	Mouse	HEK293 Cells
	Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of ...
TMPY-04283	CD131 Protein, Rat, Recombinant (hFc) colony stimulating factor 2 recep...	Rat	HEK293 Cells
	CD131 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.1 kDa and the accession number is Q78ZF5.
TMPY-02466	GM-CSF/CSF2 Protein, Human, Recombinant (His) colony stimulating factor 2 (...	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is P04141.
TMPY-05236	GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated CSF2,GMCSF,GM-CSF,集落刺激因子,colony stimulating	Human	HEK293 Cells
	GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141.
TMPY-00813	G-CSF Protein, Human, Recombinant (hFc) CSF3OS,C17orf33,colony stimulating fac...	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P09919-2.
TMPY-00814	CSF3R/G-CSFR Protein, Human, Recombinant (hFc) G-CSF R,GCSFR,CD114,CSF3R,colony stimulating	Human	HEK293 Cells
	CSF3R/G-CSFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.3 kDa and the accession number is Q99062-1.
TMPY-03631	GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc) GMCSF,Csfgm,集落刺激因子,colony stimulating ...	Mouse	HEK293 Cells
	GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01587.
TMPY-00816	GM-CSFR alpha Protein, Human, Recombinant (hFc) CSF2RAX,CSF2R,CD116,CSF2RY,GM-CSF-R-α,GM-CSF-R-alpha,GM-CSF ...	Human	HEK293 Cells
	GM-CSFR alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.2 kDa and the accession number is P15509-1.
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) Oncostatin-M,OSM	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac...
TMPK-00876	G-CSFR/CD114 Protein, Mouse, Recombinant (His) CD114,G CSF R,G-CSF-R,G-CSF R,CSF3R,GCSFR,Csfgr	Mouse	HEK293 Cells
	The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires the recruitment of cytosolic protein tyrosine kinases (PTKs) to transduce its signal.
TMPY-01299	GMF gamma/GMFG Protein, Human, Recombinant (His) glia maturation factor, γ,glia maturation facto...	Human	E. coli
	The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells. GMFG expression independently predicts poorer prognosis in patients with EOC. Ectopic overexpression of GMFG contributes to the malignant biological behavior of ovarian cancer cells.
TMPY-02577	NAMPT Protein, Human, Recombinant (His & GST) VISFATIN,PBEF,PBEF1,1110035O14Rik,VF,nicotinamide phosphorib...	Human	Baculovirus Insect Cells
	Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is...
TMPJ-00080	IL-11 Protein, Human, Recombinant (P. pastoris) 白细胞介素,Oprelvekin,Adipogenesis Inhibitory Factor,白介素...	Human	P. pastoris (Yeast)
	Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its recepto...
TMPY-04421	FES Protein, Human, Recombinant (His & GST) FPS,FES proto-oncogene, tyrosine kinase	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and oneSH2 domain. FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. FES is observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-6. T...

重组蛋白

GM-CSF/CSF2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03713

Species: Rat

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-01465

Species: Human

Expression System: E. coli

G-CSF Protein, Human, Recombinant

Cat.No: TMPY-04829

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00750

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03662

Species: Mouse

Expression System: HEK293 Cells

G-CSF Protein, Mouse, Recombinant

Cat.No: TMPY-05636

Species: Mouse

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant

Cat.No: TMPY-03858

Species: Human

Expression System: HEK293 Cells

CSF3R/G-CSFR Protein, Human, Recombinant (His)

Cat.No: TMPY-02312

Species: Human

Expression System: HEK293 Cells

CD131 Protein, Human, Recombinant (His)

Cat.No: TMPY-01650

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Mouse, Recombinant

Cat.No: TMPY-04114

Species: Mouse

Expression System: HEK293 Cells

GM-CSFR alpha Protein, Human, Recombinant (His)

Cat.No: TMPY-01065

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04036

Species: Rat

Expression System: HEK293 Cells

G-CSF Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00091

Species: Mouse

Expression System: HEK293 Cells

CD131 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04283

Species: Rat

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02466

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05236

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00813

Species: Human

Expression System: HEK293 Cells

CSF3R/G-CSFR Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00814

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03631

Species: Mouse

Expression System: HEK293 Cells

GM-CSFR alpha Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00816

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPJ-01467

Species: Human

Expression System: E. coli

G-CSFR/CD114 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00876

Species: Mouse

Expression System: HEK293 Cells

GMF gamma/GMFG Protein, Human, Recombinant (His)

Cat.No: TMPY-01299

Species: Human

Expression System: E. coli

NAMPT Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02577

Species: Human

Expression System: Baculovirus Insect Cells

IL-11 Protein, Human, Recombinant (P. pastoris)

Cat.No: TMPJ-00080

Species: Human

Expression System: P. pastoris (Yeast)

FES Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04421

Species: Human

Expression System: Baculovirus Insect Cells

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